Project Description

The aim is to develop rapid diagnostic tools for cancer. Highly parallelized mechanical sensors are used to investigate biopsy samples in a fast and reliable way. A large number of force vs. distance curves is acquired on the biopsy sample to get enough statistics for a representative value of the elasticity (Young’s modulus) of the cells under investigation.  

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Fast diagnostics of BRAF mutations in biopsies from malignant melanoma
François Huber, Hans Peter Lang, Kathrin Glatz, Donata Rimoldi, Ernst Meyer, Christoph Gerber
Nano Letters 2016, 16, 5373-5377

Piezoresistive membrane surface stress sensors for characterization of breath samples of head & neck cancer patients
Hans Peter Lang, Frédéric Loizeau, Agnès Hiou, Jean-Paul Rivals, Pedro Romero, Terunobu Akiyama, Christoph Gerber, Ernst Meyer


Piezoresistive membrane surface stress sensors for characterization of breath samples of head and neck cancer patients
Hans Peter Lang, Frédéric Loizeau, Agnès Hiou, Jean-Paul Rivals, Pedro Romero, Terunobu Akiyama, Christoph Gerber, Ernst Meyer
Sensors 2016, 16, 1149; doi:10.3390/s16071149


Emilsson, G., Schoch, R. L., Oertle, P., Xiong, K., Lim, Roderick Y., & Dahlin, A. B.
Applied Surface Science, 396, 384-392


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Diagnosis of HER2 amplification in biopsies from breast cancer using nanomechanical biosensors
François Huber, Hans Peter Lang, Marija Plodinec, Ernst Meyer, Christoph Gerber

Nanomechanical profiling of breast cancer
Marija Plodinec, Christian Raez, Philipp Oertle, Daphne Asgeirsson, Marko Loparic, Ellen C. Obermann and Roderick Y.H. Lim

Software design and device development for cantilever array deflection read-out in the FlexAFM head
Paolo Oliva, Hans Peter Lang, François Huber, Andreas Tonin, Lukas Howald, Dominik Brändlin, Terunobu Akiyama, Christoph Gerber, Ernst Meyer

BRAF mutational analysis of malignant melanoma biopsies
François Huber, Hans Peter Lang, Katharina Glatz, Donata Rimoldi, Ernst Meyer, Christoph Gerber


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