Asthma is a chronic disease affecting over 300 million people worldwide, in which contraction of bronchial smooth muscle causes breathing difficulties. Despite a vast amount of information on related genes, gene products and signaling pathways, asthma is very poorly understood, with existing medication alleviating only the immediate symptoms of the disease. A high-throughput in vitro model of smooth muscle function is needed to allow genes to be related to disease mechanisms. [read on]
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